Initiation of MLL-rearranged AML is dependent on C/EBPα

MLL-fusion proteins are potent inducers of oncogenic transformation, and their expression is considered to be the main oncogenic driving force in ∼10% of human acute myeloid leukemia (AML) patients. These oncogenic fusion proteins are responsible for the initiation of a downstream transcriptional pr...

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Detalles Bibliográficos
Autores principales: Ohlsson, Ewa, Hasemann, Marie Sigurd, Willer, Anton, Lauridsen, Felicia Kathrine Bratt, Rapin, Nicolas, Jendholm, Johan, Porse, Bo Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892979/
https://www.ncbi.nlm.nih.gov/pubmed/24367003
http://dx.doi.org/10.1084/jem.20130932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892979/
https://www.ncbi.nlm.nih.gov/pubmed/24367003
http://dx.doi.org/10.1084/jem.20130932

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