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Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation

Zebrafish-based chemical screening has recently emerged as a rapid and efficient method to identify important compounds that modulate specific biological processes and to test the therapeutic efficacy in disease models, including cancer. In leukemia, the ablation of leukemia stem cells (LSCs) is nec...

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Detalles Bibliográficos
Autores principales: Zhang, Beibei, Shimada, Yasuhito, Kuroyanagi, Junya, Umemoto, Noriko, Nishimura, Yuhei, Tanaka, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893211/
https://www.ncbi.nlm.nih.gov/pubmed/24454867
http://dx.doi.org/10.1371/journal.pone.0085439