Rapid optimization and prototyping for therapeutic antibody-like molecules

Multispecific antibody-like molecules have the potential to advance the standard-of-care in many human diseases. The design of therapeutic molecules in this class, however, has proven to be difficult and, despite significant successes in preclinical research, only one trivalent antibody, catumaxomab...

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Detalles Bibliográficos
Autores principales: Xu, Lihui, Kohli, Neeraj, Rennard, Rachel, Jiao, Yang, Razlog, Maja, Zhang, Kathy, Baum, Jason, Johnson, Bryan, Tang, Jian, Schoeberl, Birgit, Fitzgerald, Jonathan, Nielsen, Ulrik, Lugovskoy, Alexey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893234/
https://www.ncbi.nlm.nih.gov/pubmed/23392215
http://dx.doi.org/10.4161/mabs.23363

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