Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model

Severe lower respiratory tract infection in infants and small children is commonly caused by respiratory syncytial virus (RSV). Palivizumab (Synagis(®)), a humanized IgG(1) monoclonal antibody (mAb) approved for RSV immunoprophylaxis in at-risk neonates, is highly effective, but pharmacoeconomic ana...

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Detalles Bibliográficos
Autores principales: Zeitlin, Larry, Bohorov, Ognian, Bohorova, Natasha, Hiatt, Andrew, Kim, Do H., Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Barnard, Dale L., Bates, John T., Crowe, James E., Piedra, Pedro A., Gilbert, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893236/
https://www.ncbi.nlm.nih.gov/pubmed/23396091
http://dx.doi.org/10.4161/mabs.23281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893236/
https://www.ncbi.nlm.nih.gov/pubmed/23396091
http://dx.doi.org/10.4161/mabs.23281

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