Lipid Metabolism, Oxidative Stress and Cell Death Are Regulated by PKC Delta in a Dietary Model of Nonalcoholic Steatohepatitis

Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet model of NASH, yet its pathophysiological importanc...

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Detalles Bibliográficos
Autores principales: Greene, Michael W., Burrington, Christine M., Lynch, Darin T., Davenport, Samantha K., Johnson, Andrew K., Horsman, Melissa J., Chowdhry, Saleem, Zhang, Jian, Sparks, Janet D., Tirrell, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893275/
https://www.ncbi.nlm.nih.gov/pubmed/24454937
http://dx.doi.org/10.1371/journal.pone.0085848

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