Flagellin Treatment Prevents Increased Susceptibility to Systemic Bacterial Infection after Injury by Inhibiting Anti-Inflammatory IL-10+ IL-12- Neutrophil Polarization

Severe trauma renders patients susceptible to infection. In sepsis, defective bacterial clearance has been linked to specific deviations in the innate immune response. We hypothesized that innate immune modulations observed during sepsis also contribute to increased bacterial susceptibility after se...

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Detalles Bibliográficos
Autores principales: Neely, Crystal J., Kartchner, Laurel B., Mendoza, April E., Linz, Brandon M., Frelinger, Jeffrey A., Wolfgang, Matthew C., Maile, Robert, Cairns, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893295/
https://www.ncbi.nlm.nih.gov/pubmed/24454904
http://dx.doi.org/10.1371/journal.pone.0085623

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