Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

BACKGROUND: Rupture of a saccular intracranial aneurysm (sIA) causes an often fatal subarachnoid hemorrhage (SAH). Why some sIAs rupture remains unknown. Since sIA walls bear some histological similarities with early atherosclerotic lesions, we hypothesized that accumulation and oxidation of lipids...

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Detalles Bibliográficos
Autores principales: Frösen, Juhana, Tulamo, Riikka, Heikura, Tommi, Sammalkorpi, Sini, Niemelä, Mika, Hernesniemi, Juha, Levonen, Anna-Liisa, Hörkkö, Sohvi, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893371/
https://www.ncbi.nlm.nih.gov/pubmed/24252658
http://dx.doi.org/10.1186/2051-5960-1-71

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