Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein

BACKGROUND: α-Synuclein (αS) is the major component of several types of brain inclusions including Lewy bodies, a hallmark of Parkinson’s disease. Aberrant aggregation of αS also is associated with cellular demise in multiple neurologic disorders collectively referred to as synucleinopathies. Recent...

Descripción completa

Detalles Bibliográficos
Autores principales: Sacino, Amanda N, Brooks, Mieu, McGarvey, Nicholas H, McKinney, Alex B, Thomas, Michael A, Levites, Yona, Ran, Yong, Golde, Todd E, Giasson, Benoit I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893388/
https://www.ncbi.nlm.nih.gov/pubmed/24252149
http://dx.doi.org/10.1186/2051-5960-1-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893388/
https://www.ncbi.nlm.nih.gov/pubmed/24252149
http://dx.doi.org/10.1186/2051-5960-1-38

Ejemplares similares