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Pathological assessments for the presence of hexanucleotide repeat expansions in C9ORF72 in Alzheimer’s disease

BACKGROUND: We have sought histological evidence, using TDP-43 and p62 immunohistochemistry, for the presence of expansions in C9ORF72 among 200 patients with pathologically confirmed AD. RESULTS: We noted TDP-43 pathological changes in hippocampus and temporal cortex in 45 (22.5%) of these patients...

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Detalles Bibliográficos
Autores principales:	Davidson, Yvonne S, Robinson, Andrew C, Snowden, Julie S, Mann, David MA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893394/ https://www.ncbi.nlm.nih.gov/pubmed/24252571 http://dx.doi.org/10.1186/2051-5960-1-50

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