Cargando…
Dominant negative connexin26 mutation R75W causing severe hearing loss influences normal programmed cell death in postnatal organ of Corti
BACKGROUND: The greater epithelial ridge (GER) is a developmental structure in the maturation of the organ of Corti. Situated near the inner hair cells of neonatal mice, the GER undergoes a wave of apoptosis after postnatal day 8 (P8). We evaluated the GER from P8 to P12 in transgenic mice that carr...
Autores principales: | Inoshita, Ayako, Karasawa, Keiko, Funakubo, Megumi, Miwa, Asuka, Ikeda, Katsuhisa, Kamiya, Kazusaku |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893426/ https://www.ncbi.nlm.nih.gov/pubmed/24387126 http://dx.doi.org/10.1186/1471-2156-15-1 |
Ejemplares similares
-
Degradation and modification of cochlear gap junction proteins in the early development of age-related hearing loss
por: Tajima, Shori, et al.
Publicado: (2020) -
Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice
por: Anzai, Takashi, et al.
Publicado: (2015) -
Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness
por: Kidokoro, Yoshinobu, et al.
Publicado: (2014) -
Organ of Corti vibrations are dominated by longitudinal motion in vivo
por: Meenderink, Sebastiaan W. F., et al.
Publicado: (2022) -
Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice
por: Zhang, Li, et al.
Publicado: (2022)