MCP-1/CCR2 signaling-mediated astrocytosis is accelerated in a transgenic mouse model of SOD1-mutated familial ALS

BACKGROUND: Emerging evidence suggests that innate immunity and increased oxidative stress contribute to pathomechanisms in amyotrophic lateral sclerosis (ALS). The aim of the present study was to verify the involvement of monocyte chemoattractant protein-1 (MCP-1) and its specific CC chemokine rece...

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Detalles Bibliográficos
Autores principales: Kawaguchi-Niida, Motoko, Yamamoto, Tomoko, Kato, Yoichiro, Inose, Yuri, Shibata, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893446/
https://www.ncbi.nlm.nih.gov/pubmed/24252211
http://dx.doi.org/10.1186/2051-5960-1-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893446/
https://www.ncbi.nlm.nih.gov/pubmed/24252211
http://dx.doi.org/10.1186/2051-5960-1-21

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