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Differential effects of PDCD4 depletion on protein synthesis in myoblast and myotubes

BACKGROUND: Reduced muscle mass is a hallmark of metabolic diseases like diabetes and cancer. The mammalian (mechanistic) target of rapamycin complex 1/S6 kinase 1 (mTORC1/S6K1) pathway is critical to the regulation of muscle protein synthesis and mass but its mechanism of action is not completely u...

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Detalles Bibliográficos
Autores principales:	Kakade, Dhanshri, Islam, Nushaba, Maeda, Naomi, Adegoke, Olasunkanmi A J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893489/ https://www.ncbi.nlm.nih.gov/pubmed/24405715 http://dx.doi.org/10.1186/1471-2121-15-2

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