Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma

BACKGROUND: High frequencies of the BRAF V600E mutation have been reported in pleomorphic xanthoastrocytoma (PXA). Recently, a BRAF V600E mutation-specific antibody has been developed and validated. We evaluated the immunohistochemical (IHC) detection of BRAF V600E mutation in PXA by comparing to go...

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Detalles Bibliográficos
Autores principales: Ida, Cristiane M, Vrana, Julie A, Rodriguez, Fausto J, Jentoft, Mark E, Caron, Alissa A, Jenkins, Sarah M, Giannini, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893490/
https://www.ncbi.nlm.nih.gov/pubmed/24252190
http://dx.doi.org/10.1186/2051-5960-1-20

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