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Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination

BACKGROUND: Calreticulin (CRT) is a chaperone protein, which aids correct folding of glycosylated proteins in the endoplasmic reticulum (ER). Under conditions of ER stress, CRT is upregulated and may be displayed on the surface of cells or be secreted. This ‘ecto-CRT’ may activate the innate immune...

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Detalles Bibliográficos
Autores principales:	Ní Fhlathartaigh, Mary, McMahon, Jill, Reynolds, Richard, Connolly, David, Higgins, Eibhlín, Counihan, Timothy, FitzGerald, Una
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893522/ https://www.ncbi.nlm.nih.gov/pubmed/24252779 http://dx.doi.org/10.1186/2051-5960-1-37

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