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Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS

BACKGROUND: We examined the association of alcohol use disorders (AUD) with adherence to and health-related quality of life (HRQOL) outcomes of antiretroviral treatment (ART) for HIV/AIDS patients. METHODS: A cross-sectional multi-site survey was conducted in 468 drug users and 648 non-drug users (a...

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Autores principales: Tran, Bach Xuan, Nguyen, Long Thanh, Do, Cuong Duy, Nguyen, Quyen Le, Maher, Rachel Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893525/
https://www.ncbi.nlm.nih.gov/pubmed/24411007
http://dx.doi.org/10.1186/1471-2458-14-27
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author Tran, Bach Xuan
Nguyen, Long Thanh
Do, Cuong Duy
Nguyen, Quyen Le
Maher, Rachel Marie
author_facet Tran, Bach Xuan
Nguyen, Long Thanh
Do, Cuong Duy
Nguyen, Quyen Le
Maher, Rachel Marie
author_sort Tran, Bach Xuan
collection PubMed
description BACKGROUND: We examined the association of alcohol use disorders (AUD) with adherence to and health-related quality of life (HRQOL) outcomes of antiretroviral treatment (ART) for HIV/AIDS patients. METHODS: A cross-sectional multi-site survey was conducted in 468 drug users and 648 non-drug users (age: 35.4 ± 7.0 years; 63.8% male) in 3 epicentres of Vietnam. AUD, ART adherence, and HRQOL were measured using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C), the self-reported Visual Analogue Scale (VAS), and the World Health Organization Quality of Life instrument (WHOQOL-HIV BREF). RESULTS: 35.0% of drug users were hazardous drinkers, compared to 25.9% of non-drug users. 22.3% of drug users engaged in binge drinking, and 25.9% reported suboptimal ART adherence. Adjusting for propensity scores of AUD, patients who had either at-risk or binge drinking behaviour were about twice as likely to be treatment non-adherent as those who did not have AUD. Hazardous drinkers reported small to medium decrements in the Performance, Physical, Social, Spirituality, and Environment quality of life domains. Binge drinkers had a slightly higher score in Social dimension. CONCLUSION: AUD is prevalent and negatively affecting adherence to and HRQOL outcomes of ART services in injection-driven HIV epidemics. Screening and intervention are recommended for AUD, especially during the stable periods of ART. Other social and psychological interventions might also enhance patients’ responses to and outcomes of ART in Vietnam.
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spelling pubmed-38935252014-01-27 Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS Tran, Bach Xuan Nguyen, Long Thanh Do, Cuong Duy Nguyen, Quyen Le Maher, Rachel Marie BMC Public Health Research Article BACKGROUND: We examined the association of alcohol use disorders (AUD) with adherence to and health-related quality of life (HRQOL) outcomes of antiretroviral treatment (ART) for HIV/AIDS patients. METHODS: A cross-sectional multi-site survey was conducted in 468 drug users and 648 non-drug users (age: 35.4 ± 7.0 years; 63.8% male) in 3 epicentres of Vietnam. AUD, ART adherence, and HRQOL were measured using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C), the self-reported Visual Analogue Scale (VAS), and the World Health Organization Quality of Life instrument (WHOQOL-HIV BREF). RESULTS: 35.0% of drug users were hazardous drinkers, compared to 25.9% of non-drug users. 22.3% of drug users engaged in binge drinking, and 25.9% reported suboptimal ART adherence. Adjusting for propensity scores of AUD, patients who had either at-risk or binge drinking behaviour were about twice as likely to be treatment non-adherent as those who did not have AUD. Hazardous drinkers reported small to medium decrements in the Performance, Physical, Social, Spirituality, and Environment quality of life domains. Binge drinkers had a slightly higher score in Social dimension. CONCLUSION: AUD is prevalent and negatively affecting adherence to and HRQOL outcomes of ART services in injection-driven HIV epidemics. Screening and intervention are recommended for AUD, especially during the stable periods of ART. Other social and psychological interventions might also enhance patients’ responses to and outcomes of ART in Vietnam. BioMed Central 2014-01-10 /pmc/articles/PMC3893525/ /pubmed/24411007 http://dx.doi.org/10.1186/1471-2458-14-27 Text en Copyright © 2014 Tran et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tran, Bach Xuan
Nguyen, Long Thanh
Do, Cuong Duy
Nguyen, Quyen Le
Maher, Rachel Marie
Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title_full Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title_fullStr Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title_full_unstemmed Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title_short Associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with HIV/AIDS
title_sort associations between alcohol use disorders and adherence to antiretroviral treatment and quality of life amongst people living with hiv/aids
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893525/
https://www.ncbi.nlm.nih.gov/pubmed/24411007
http://dx.doi.org/10.1186/1471-2458-14-27
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