Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer’s disease

BACKGROUND: Basement membranes in the walls of cerebral capillaries and arteries form a major lymphatic drainage pathway for fluid and solutes from the brain. Amyloid-β (Aβ) draining from the brain is deposited in such perivascular pathways as cerebral amyloid angiopathy (CAA) in Alzheimer's di...

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Detalles Bibliográficos
Autores principales: Carare, Roxana Octavia, Teeling, Jessica Liesbeth, Hawkes, Cheryl A, Püntener, Ursula, Weller, Roy O, Nicoll, James AR, Perry, Victor Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893559/
https://www.ncbi.nlm.nih.gov/pubmed/24252464
http://dx.doi.org/10.1186/2051-5960-1-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893559/
https://www.ncbi.nlm.nih.gov/pubmed/24252464
http://dx.doi.org/10.1186/2051-5960-1-48

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