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Identification of a neuronal transcription factor network involved in medulloblastoma development
BACKGROUND: Medulloblastomas, the most frequent malignant brain tumours affecting children, comprise at least 4 distinct clinicogenetic subgroups. Aberrant sonic hedgehog (SHH) signalling is observed in approximately 25% of tumours and defines one subgroup. Although alterations in SHH pathway genes...
Autores principales: | Łastowska, Maria, Al-Afghani, Hani, Al-Balool, Haya H, Sheth, Harsh, Mercer, Emma, Coxhead, Jonathan M, Redfern, Chris PF, Peters, Heiko, Burt, Alastair D, Santibanez-Koref, Mauro, Bacon, Chris M, Chesler, Louis, Rust, Alistair G, Adams, David J, Williamson, Daniel, Clifford, Steven C, Jackson, Michael S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893591/ https://www.ncbi.nlm.nih.gov/pubmed/24252690 http://dx.doi.org/10.1186/2051-5960-1-35 |
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