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Functions and Regulation of the PTEN Gene in Colorectal Cancer

Phosphatase and TENsin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor gene located at chromosome 10q23.31, encoding for a 403-amino acid protein that possesses both lipid and protein phosphatase activities. The main function of PTEN is to block the PI3K pathway by dephosphorylating ph...

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Detalles Bibliográficos
Autores principales: Molinari, Francesca, Frattini, Milo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893597/
https://www.ncbi.nlm.nih.gov/pubmed/24475377
http://dx.doi.org/10.3389/fonc.2013.00326

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