CSF Presenilin-1 complexes are increased in Alzheimer’s disease

BACKGROUND: Presenilin-1 (PS1) is the active component of the amyloid precursor protein cleaving γ-secretase complex. PS1 protein is a transmembrane protein containing multiple hydrophobic regions which presence in cerebrospinal fluid (CSF) has not been measured to date. This study assesses whether...

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Detalles Bibliográficos
Autores principales: García-Ayllón, María-Salud, Campanari, María-Letizia, Brinkmalm, Gunnar, Rábano, Alberto, Alom, Jordi, Saura, Carlos A, Andreasen, Niels, Blennow, Kaj, Sáez-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893612/
https://www.ncbi.nlm.nih.gov/pubmed/24252417
http://dx.doi.org/10.1186/2051-5960-1-46

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