How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?

There is significant interest in delivering precisely targeted small-volume radiation treatments, in the pre-clinical setting, to study dose-volume relationships with tumor control and normal tissue damage. In this work we investigate the IGRT targeting accuracy of the XRad225Cx system from Precisio...

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Detalles Bibliográficos
Autores principales: Oldham, M, Newton, J, Rankine, L, Adamovics, J, Kirsch, D, Das, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894105/
https://www.ncbi.nlm.nih.gov/pubmed/24454521
http://dx.doi.org/10.1088/1742-6596/444/1/012070
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author Oldham, M
Newton, J
Rankine, L
Adamovics, J
Kirsch, D
Das, S
author_facet Oldham, M
Newton, J
Rankine, L
Adamovics, J
Kirsch, D
Das, S
author_sort Oldham, M
collection PubMed
description There is significant interest in delivering precisely targeted small-volume radiation treatments, in the pre-clinical setting, to study dose-volume relationships with tumor control and normal tissue damage. In this work we investigate the IGRT targeting accuracy of the XRad225Cx system from Precision x-Ray using high resolution 3D dosimetry techniques. Initial results revealed a significant targeting error of about 2.4mm. This error was reduced to within 0.5mm after the IGRT hardware and software had been recalibrated. The facility for 3D dosimetry was essential to gain a comprehensive understanding of the targeting error in 3D.
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spelling pubmed-38941052014-01-16 How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator? Oldham, M Newton, J Rankine, L Adamovics, J Kirsch, D Das, S J Phys Conf Ser Article There is significant interest in delivering precisely targeted small-volume radiation treatments, in the pre-clinical setting, to study dose-volume relationships with tumor control and normal tissue damage. In this work we investigate the IGRT targeting accuracy of the XRad225Cx system from Precision x-Ray using high resolution 3D dosimetry techniques. Initial results revealed a significant targeting error of about 2.4mm. This error was reduced to within 0.5mm after the IGRT hardware and software had been recalibrated. The facility for 3D dosimetry was essential to gain a comprehensive understanding of the targeting error in 3D. 2013 /pmc/articles/PMC3894105/ /pubmed/24454521 http://dx.doi.org/10.1088/1742-6596/444/1/012070 Text en http://creativecommons.org/licenses/by/3.0/ Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Published under licence by IOP Publishing Ltd
spellingShingle Article
Oldham, M
Newton, J
Rankine, L
Adamovics, J
Kirsch, D
Das, S
How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title_full How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title_fullStr How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title_full_unstemmed How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title_short How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?
title_sort how accurate is image guided radiation therapy (igrt) delivered with a micro-irradiator?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894105/
https://www.ncbi.nlm.nih.gov/pubmed/24454521
http://dx.doi.org/10.1088/1742-6596/444/1/012070
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