Cargando…

Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity

Since the discovery of tumour initiating cells (TICs) in solid tumours, studies focussing on their role in cancer initiation and progression have abounded. The biological interrogation of these cells continues to yield volumes of information on their pro-tumourigenic behaviour, but actionable genera...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Jacob G., Hjelmeland, Anita B., Chinnaiyan, Prakash, Anderson, Alexander R. A., Basanta, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894166/
https://www.ncbi.nlm.nih.gov/pubmed/24453958
http://dx.doi.org/10.1371/journal.pcbi.1003433