Mice Lacking NMDA Receptors in Parvalbumin Neurons Display Normal Depression-Related Behavior and Response to Antidepressant Action of NMDAR Antagonists

The underlying circuit imbalance in major depression remains unknown and current therapies remain inadequate for a large group of patients. Discovery of the rapid antidepressant effects of ketamine - an NMDA receptor (NMDAR) antagonist – has linked the glutamatergic system to depression. Interesting...

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Detalles Bibliográficos
Autores principales: Pozzi, Laura, Dorocic, Iskra Pollak, Wang, Xinming, Carlén, Marie, Meletis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894182/
https://www.ncbi.nlm.nih.gov/pubmed/24454710
http://dx.doi.org/10.1371/journal.pone.0083879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894182/
https://www.ncbi.nlm.nih.gov/pubmed/24454710
http://dx.doi.org/10.1371/journal.pone.0083879

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