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Mice Lacking NMDA Receptors in Parvalbumin Neurons Display Normal Depression-Related Behavior and Response to Antidepressant Action of NMDAR Antagonists
The underlying circuit imbalance in major depression remains unknown and current therapies remain inadequate for a large group of patients. Discovery of the rapid antidepressant effects of ketamine - an NMDA receptor (NMDAR) antagonist – has linked the glutamatergic system to depression. Interesting...
Autores principales: | Pozzi, Laura, Dorocic, Iskra Pollak, Wang, Xinming, Carlén, Marie, Meletis, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894182/ https://www.ncbi.nlm.nih.gov/pubmed/24454710 http://dx.doi.org/10.1371/journal.pone.0083879 |
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