Cargando…

Pooled Screening for Synergistic Interactions Subject to Blocking and Noise

The complex molecular networks in the cell can give rise to surprising interactions: gene deletions that are synthetically lethal, gene overexpressions that promote stemness or differentiation, synergistic drug interactions that heighten potency. Yet, the number of actual interactions is dwarfed by...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Kyle, Precup, Doina, Perkins, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894196/
https://www.ncbi.nlm.nih.gov/pubmed/24454940
http://dx.doi.org/10.1371/journal.pone.0085864