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Gammaherpesviral Gene Expression and Virion Composition Are Broadly Controlled by Accelerated mRNA Degradation

Lytic gammaherpesvirus infection restricts host gene expression by promoting widespread degradation of cytoplasmic mRNA through the activity of the viral endonuclease SOX. Though generally assumed to be selective for cellular transcripts, the extent to which SOX impacts viral mRNA stability has rema...

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Detalles Bibliográficos
Autores principales:	Abernathy, Emma, Clyde, Karen, Yeasmin, Rukhsana, Krug, Laurie T., Burlingame, Al, Coscoy, Laurent, Glaunsinger, Britt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894220/ https://www.ncbi.nlm.nih.gov/pubmed/24453974 http://dx.doi.org/10.1371/journal.ppat.1003882

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