The Diarylheptanoid Hirsutenone Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin via Modulation of Apoptosis-inducing Factor and X-linked Inhibitor of Apoptosis

Cisplatin (CDDP) and its derivatives are considered first-line treatments for ovarian cancer (OVCA). However, despite initial results that often appear promising, in most cases patients will return with recurrent disease that fails to respond to further chemotherapy. We assayed a number of food phyt...

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Detalles Bibliográficos
Autores principales: Farrand, Lee, Kim, Ji Young, Byun, Sanguine, Im-aram, Akechai, Lee, Jihoon, Suh, Jeong-Yong, Lee, Ki-Won, Lee, Hyong Joo, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894349/
https://www.ncbi.nlm.nih.gov/pubmed/24247248
http://dx.doi.org/10.1074/jbc.M113.513879

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