Impact of age-associated increase in 2′-O-methylation of miRNAs on aging and neurodegeneration in Drosophila

MicroRNAs (miRNAs) are 20- to ∼24-nucleotide (nt) small RNAs that impact a variety of biological processes, from development to age-associated events. To study the role of miRNAs in aging, studies have profiled the levels of miRNAs with time. However, evidence suggests that miRNAs show heterogeneity...

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Detalles Bibliográficos
Autores principales: Abe, Masashi, Naqvi, Ammar, Hendriks, Gert-Jan, Feltzin, Virzhiniya, Zhu, Yongqing, Grigoriev, Andrey, Bonini, Nancy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894412/
https://www.ncbi.nlm.nih.gov/pubmed/24395246
http://dx.doi.org/10.1101/gad.226654.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894412/
https://www.ncbi.nlm.nih.gov/pubmed/24395246
http://dx.doi.org/10.1101/gad.226654.113

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