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Impact of age-associated increase in 2′-O-methylation of miRNAs on aging and neurodegeneration in Drosophila
MicroRNAs (miRNAs) are 20- to ∼24-nucleotide (nt) small RNAs that impact a variety of biological processes, from development to age-associated events. To study the role of miRNAs in aging, studies have profiled the levels of miRNAs with time. However, evidence suggests that miRNAs show heterogeneity...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894412/ https://www.ncbi.nlm.nih.gov/pubmed/24395246 http://dx.doi.org/10.1101/gad.226654.113 |