Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient

Reactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We repo...

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Detalles Bibliográficos
Autores principales: Chordia, Poorvi, Chandrasekar, Pranatharthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894844/
https://www.ncbi.nlm.nih.gov/pubmed/24455117
http://dx.doi.org/10.4084/MJHID.2014.008
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author Chordia, Poorvi
Chandrasekar, Pranatharthi
author_facet Chordia, Poorvi
Chandrasekar, Pranatharthi
author_sort Chordia, Poorvi
collection PubMed
description Reactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We report a case of severe HHV-6 encephalitis with viremia in an allogeneic peripheral stem cell transplant recipient who presented with status epilepticus unresponsive to antiepileptic therapy. With intravenous ganciclovir and supportive care, the patient’s condition improved. Awareness of HHV-6 infection in stem cell transplant recipients may help with early diagnosis and improved outcome.
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spelling pubmed-38948442014-01-22 Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient Chordia, Poorvi Chandrasekar, Pranatharthi Mediterr J Hematol Infect Dis Case Report Reactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We report a case of severe HHV-6 encephalitis with viremia in an allogeneic peripheral stem cell transplant recipient who presented with status epilepticus unresponsive to antiepileptic therapy. With intravenous ganciclovir and supportive care, the patient’s condition improved. Awareness of HHV-6 infection in stem cell transplant recipients may help with early diagnosis and improved outcome. Università Cattolica del Sacro Cuore 2014-01-01 /pmc/articles/PMC3894844/ /pubmed/24455117 http://dx.doi.org/10.4084/MJHID.2014.008 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chordia, Poorvi
Chandrasekar, Pranatharthi
Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title_full Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title_fullStr Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title_full_unstemmed Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title_short Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
title_sort status epilepticus due to severe hhv-6 encephalitis in an allogeneic stem cell transplant recipient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894844/
https://www.ncbi.nlm.nih.gov/pubmed/24455117
http://dx.doi.org/10.4084/MJHID.2014.008
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AT chandrasekarpranatharthi statusepilepticusduetoseverehhv6encephalitisinanallogeneicstemcelltransplantrecipient

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