Cargando…

Involvement of Suppressive B-Lymphocytes in the Mechanism of Tolerogenic Dendritic Cell Reversal of Type 1 Diabetes in NOD Mice

The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese Diabetic (NOD) mouse strain. Co-culture experiments...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Caro, Valentina, Phillips, Brett, Engman, Carl, Harnaha, Jo, Trucco, Massimo, Giannoukakis, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894962/ https://www.ncbi.nlm.nih.gov/pubmed/24465383 http://dx.doi.org/10.1371/journal.pone.0083575

Ejemplares similares

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients
por: Giannoukakis, Nick, et al.
Publicado: (2011)

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy
por: Phillips, Brett Eugene, et al.
Publicado: (2019)

Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice
por: Garciafigueroa, Yesica, et al.
Publicado: (2021)

Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease
por: Phillips, Brett Eugene, et al.
Publicado: (2017)

Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice
por: Engman, Carl, et al.
Publicado: (2018)

Tolerogenic dendritic cells in type 1 diabetes: no longer a concept
por: Giannoukakis, Nick
Publicado: (2023)

Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same?
por: Phillips, Brett, et al.
Publicado: (2011)

Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist
por: Phillips, Brett E., et al.
Publicado: (2022)

Immunotherapy with Tolerogenic Dendritic Cells Alone or in Combination with Rapamycin Does Not Reverse Diabetes in NOD Mice
por: Pujol-Autonell, Irma, et al.
Publicado: (2013)

Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation
por: Phillips, Brett E., et al.
Publicado: (2021)

It’s Time to Bring Dendritic Cell Therapy to Type 1 Diabetes
por: Creusot, Rémi J., et al.
Publicado: (2014)

Tolerogenic dendritic cells suppress titanium particle-induced inflammation
por: Wang, Wenzhao, et al.
Publicado: (2021)

Tolerogenic dendritic cell-based immunotherapy
por: Chang, Kiyuk, et al.
Publicado: (2017)

CXCL4 suppresses tolerogenic immune signature of monocyte‐derived dendritic cells
por: Silva‐Cardoso, Sandra C., et al.
Publicado: (2020)

Regulatory Multitasking of Tolerogenic Dendritic Cells – Lessons Taken from Vitamin D3-Treated Tolerogenic Dendritic Cells
por: Nikolic, Tatjana, et al.
Publicado: (2013)

The nature of activatory and tolerogenic dendritic cell-derived signal II
por: Bakdash, Ghaith, et al.
Publicado: (2013)

Tolerogenic function of Blimp-1 in dendritic cells
por: Kim, Sun Jung, et al.
Publicado: (2011)

Tolerogenic function of Blimp-1 in dendritic cells
por: Kim, Sun Jung, et al.
Publicado: (2012)

Tolerogenic and Activatory Plasmacytoid Dendritic Cells in Autoimmunity
por: Guéry, Leslie, et al.
Publicado: (2013)

Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications
por: Yoo, Seungbo, et al.
Publicado: (2016)

Metabolism Is Central to Tolerogenic Dendritic Cell Function
por: Sim, Wen Jing, et al.
Publicado: (2016)

Ethyl Pyruvate Induces Tolerogenic Dendritic Cells
por: Djedovic, Neda, et al.
Publicado: (2019)

Tolerogenic Dendritic Cell-Based Approaches in Autoimmunity
por: Passeri, Laura, et al.
Publicado: (2021)

Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity
por: Nam, Ji-Hee, et al.
Publicado: (2021)

TGF-β Suppresses β-Catenin-Dependent Tolerogenic Activation Program in Dendritic Cells
por: Vander Lugt, Bryan, et al.
Publicado: (2011)

HIV-1 induction of tolerogenic dendritic cells is mediated by cellular interaction with suppressive T cells
por: Svanberg, Cecilia, et al.
Publicado: (2022)

Lactoferrin Induces Tolerogenic Bone Marrow-Derived Dendritic Cells
por: Park, Hui-Won, et al.
Publicado: (2020)

Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b
por: Zerif, Echarki, et al.
Publicado: (2020)

Rel B‐modified dendritic cells possess tolerogenic phenotype and functions on lupus splenic lymphocytes in vitro
por: Wu, Haijing, et al.
Publicado: (2016)

Cell therapy using tolerogenic dendritic cells in transplantation
por: Moreau, Aurélie, et al.
Publicado: (2012)

Tolerogenic Dendritic Cells for Regulatory T Cell Induction in Man
por: Raker, Verena K., et al.
Publicado: (2015)

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
por: Bell, G M, et al.
Publicado: (2017)

Induction of Tolerogenic Dendritic Cells by Endogenous Biomolecules: An Update
por: Švajger, Urban, et al.
Publicado: (2018)

Tolerogenic Dendritic Cells: The Pearl of Immunotherapy in Organ Transplantation
por: Zhuang, Quan, et al.
Publicado: (2020)

Dust-mite-derived protein disulfide isomerase suppresses airway allergy by inducing tolerogenic dendritic cells
por: Liu, Xiaoyu, et al.
Publicado: (2021)

Uncoupling hepatic insulin resistance – hepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease in type 2 diabetes
por: Niranjan, Sitara, et al.
Publicado: (2023)

Comparative study of clinical grade human tolerogenic dendritic cells
por: Naranjo-Gómez, M, et al.
Publicado: (2011)

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis
por: Harry, Rachel A, et al.
Publicado: (2010)

Costimulatory Molecules on Immunogenic Versus Tolerogenic Human Dendritic Cells
por: Hubo, Mario, et al.
Publicado: (2013)

The Nature of Activatory and Tolerogenic Dendritic Cell-Derived Signal 2
por: Granucci, Francesca, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_l5emoilo4kbo8p74altrv1pcta