Angiopoietin-Like Protein 2 Induced by Mechanical Stress Accelerates Degeneration and Hypertrophy of the Ligamentum Flavum in Lumbar Spinal Canal Stenosis

Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS). Angiopoietin-like protein 2 (Angptl2) is a chronic inflammatory mediator induced under various...

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Detalles Bibliográficos
Autores principales: Nakamura, Takayuki, Okada, Tatsuya, Endo, Motoyoshi, Kadomatsu, Tsuyoshi, Taniwaki, Takuya, Sei, Akira, Odagiri, Haruki, Masuda, Tetsuro, Fujimoto, Toru, Nakamura, Takafumi, Oike, Yuichi, Mizuta, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894965/
https://www.ncbi.nlm.nih.gov/pubmed/24465594
http://dx.doi.org/10.1371/journal.pone.0085542

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