Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways

Arctigenin, a lignan-derived compound, is a constituent of the seeds of Arctium lappa. Arctigenin was previously shown to inhibit osteoclastogenesis; however, this inhibitory mechanism has yet to be elucidated. Here, we showed that arctigenin inhibited the action of nuclear factor of activated T-cel...

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Detalles Bibliográficos
Autores principales: Yamashita, Teruhito, Uehara, Shunsuke, Udagawa, Nobuyuki, Li, Feng, Kadota, Shigetoshi, Esumi, Hiroyasu, Kobayashi, Yasuhiro, Takahashi, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895012/
https://www.ncbi.nlm.nih.gov/pubmed/24465763
http://dx.doi.org/10.1371/journal.pone.0085878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895012/
https://www.ncbi.nlm.nih.gov/pubmed/24465763
http://dx.doi.org/10.1371/journal.pone.0085878

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