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Human Lactate Dehydrogenase A Inhibitors: A Molecular Dynamics Investigation
Lactate dehydrogenase A (LDHA) is an important enzyme in fermentative glycolysis, generating most energy for cancer cells that rely on anaerobic respiration even under normal oxygen concentrations. This renders LDHA a promising molecular target for the treatment of various cancers. Several efforts h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895040/ https://www.ncbi.nlm.nih.gov/pubmed/24466056 http://dx.doi.org/10.1371/journal.pone.0086365 |