Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains

BACKGROUND: Cellular differentiation and reprogramming are accompanied by changes in replication timing and 3D organization of large-scale (400 to 800 Kb) chromosomal domains (‘replication domains’), but few gene products have been identified whose disruption affects these properties. RESULTS: Here...

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Detalles Bibliográficos
Autores principales: Takebayashi, Shin-ichiro, Lei, Ienglam, Ryba, Tyrone, Sasaki, Takayo, Dileep, Vishnu, Battaglia, Dana, Gao, Xiaolin, Fang, Peng, Fan, Yong, Esteban, Miguel A, Tang, Jiong, Crabtree, Gerald R, Wang, Zhong, Gilbert, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895691/
https://www.ncbi.nlm.nih.gov/pubmed/24330833
http://dx.doi.org/10.1186/1756-8935-6-42

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