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Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis
BACKGROUND: The translocator protein (18 kDa) (TSPO) is a mitochondrial protein expressed on reactive glial cells and a biomarker for gliosis in the brain. TSPO ligands have been shown to reduce neuroinflammation in several mouse models of neurodegeneration. Here, we analyzed TSPO expression in mous...
Autores principales: | Karlstetter, Marcus, Nothdurfter, Caroline, Aslanidis, Alexander, Moeller, Katharina, Horn, Felicitas, Scholz, Rebecca, Neumann, Harald, Weber, Bernhard H F, Rupprecht, Rainer, Langmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895821/ https://www.ncbi.nlm.nih.gov/pubmed/24397957 http://dx.doi.org/10.1186/1742-2094-11-3 |
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