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Beyond radio-displacement techniques for Identification of CB(1) Ligands: The First Application of a Fluorescence-quenching Assay
Cannabinoid type 1 Receptor (CB(1)) belongs to the GPCR family and it has been targeted, so far, for the discovery of drugs aimed at the treatment of neuropathic pain, nausea, vomit, and food intake disorders. Here, we present the development of the first fluorescent assay enabling the measurement o...
Autores principales: | Bruno, Agostino, Lembo, Francesca, Novellino, Ettore, Stornaiuolo, Mariano, Marinelli, Luciana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895875/ https://www.ncbi.nlm.nih.gov/pubmed/24441508 http://dx.doi.org/10.1038/srep03757 |
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