Cargando…

Beyond radio-displacement techniques for Identification of CB(1) Ligands: The First Application of a Fluorescence-quenching Assay

Cannabinoid type 1 Receptor (CB(1)) belongs to the GPCR family and it has been targeted, so far, for the discovery of drugs aimed at the treatment of neuropathic pain, nausea, vomit, and food intake disorders. Here, we present the development of the first fluorescent assay enabling the measurement o...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruno, Agostino, Lembo, Francesca, Novellino, Ettore, Stornaiuolo, Mariano, Marinelli, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895875/
https://www.ncbi.nlm.nih.gov/pubmed/24441508
http://dx.doi.org/10.1038/srep03757

Ejemplares similares