Peripheral Primitive Neuroectodermal Tumor of the Pelvis

The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNE...

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Autores principales: Yousefi, Zohreh, Sharifhi, Nourieh, Hasanzadeh, Malihe, Mottaghi, Mansoureh, Bolandy, Somayeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895899/
https://www.ncbi.nlm.nih.gov/pubmed/24453398
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author Yousefi, Zohreh
Sharifhi, Nourieh
Hasanzadeh, Malihe
Mottaghi, Mansoureh
Bolandy, Somayeh
author_facet Yousefi, Zohreh
Sharifhi, Nourieh
Hasanzadeh, Malihe
Mottaghi, Mansoureh
Bolandy, Somayeh
author_sort Yousefi, Zohreh
collection PubMed
description The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNET cases arising in the pelvis have been reported as well. We present three cases of pelvic PNET: two cases in the ovary and one case in the broad ligament. The PNET often exhibits aggressive clinical behavior with worse outcomes than other small round cell tumors. The significant prognostic factors of the PNET include site of tumor, volume of neoplasm, and presence of metastasis. The treatment protocol is multimodal and includes local surgical treatment followed by chemotherapy. We herein describe three PNET cases as a rare entity in the pelvis. Pelvic PNETs should be included in the differential diagnosis of pelvic masses.
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spelling pubmed-38958992014-01-21 Peripheral Primitive Neuroectodermal Tumor of the Pelvis Yousefi, Zohreh Sharifhi, Nourieh Hasanzadeh, Malihe Mottaghi, Mansoureh Bolandy, Somayeh Iran J Med Sci Case Report The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNET cases arising in the pelvis have been reported as well. We present three cases of pelvic PNET: two cases in the ovary and one case in the broad ligament. The PNET often exhibits aggressive clinical behavior with worse outcomes than other small round cell tumors. The significant prognostic factors of the PNET include site of tumor, volume of neoplasm, and presence of metastasis. The treatment protocol is multimodal and includes local surgical treatment followed by chemotherapy. We herein describe three PNET cases as a rare entity in the pelvis. Pelvic PNETs should be included in the differential diagnosis of pelvic masses. Shiraz University of Medical Sciences 2014-01 /pmc/articles/PMC3895899/ /pubmed/24453398 Text en © 2014: Iranian Journal of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yousefi, Zohreh
Sharifhi, Nourieh
Hasanzadeh, Malihe
Mottaghi, Mansoureh
Bolandy, Somayeh
Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title_full Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title_fullStr Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title_full_unstemmed Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title_short Peripheral Primitive Neuroectodermal Tumor of the Pelvis
title_sort peripheral primitive neuroectodermal tumor of the pelvis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895899/
https://www.ncbi.nlm.nih.gov/pubmed/24453398
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