Peripheral Primitive Neuroectodermal Tumor of the Pelvis
The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNE...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895899/ https://www.ncbi.nlm.nih.gov/pubmed/24453398 |
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author | Yousefi, Zohreh Sharifhi, Nourieh Hasanzadeh, Malihe Mottaghi, Mansoureh Bolandy, Somayeh |
author_facet | Yousefi, Zohreh Sharifhi, Nourieh Hasanzadeh, Malihe Mottaghi, Mansoureh Bolandy, Somayeh |
author_sort | Yousefi, Zohreh |
collection | PubMed |
description | The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNET cases arising in the pelvis have been reported as well. We present three cases of pelvic PNET: two cases in the ovary and one case in the broad ligament. The PNET often exhibits aggressive clinical behavior with worse outcomes than other small round cell tumors. The significant prognostic factors of the PNET include site of tumor, volume of neoplasm, and presence of metastasis. The treatment protocol is multimodal and includes local surgical treatment followed by chemotherapy. We herein describe three PNET cases as a rare entity in the pelvis. Pelvic PNETs should be included in the differential diagnosis of pelvic masses. |
format | Online Article Text |
id | pubmed-3895899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Shiraz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-38958992014-01-21 Peripheral Primitive Neuroectodermal Tumor of the Pelvis Yousefi, Zohreh Sharifhi, Nourieh Hasanzadeh, Malihe Mottaghi, Mansoureh Bolandy, Somayeh Iran J Med Sci Case Report The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNET cases arising in the pelvis have been reported as well. We present three cases of pelvic PNET: two cases in the ovary and one case in the broad ligament. The PNET often exhibits aggressive clinical behavior with worse outcomes than other small round cell tumors. The significant prognostic factors of the PNET include site of tumor, volume of neoplasm, and presence of metastasis. The treatment protocol is multimodal and includes local surgical treatment followed by chemotherapy. We herein describe three PNET cases as a rare entity in the pelvis. Pelvic PNETs should be included in the differential diagnosis of pelvic masses. Shiraz University of Medical Sciences 2014-01 /pmc/articles/PMC3895899/ /pubmed/24453398 Text en © 2014: Iranian Journal of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yousefi, Zohreh Sharifhi, Nourieh Hasanzadeh, Malihe Mottaghi, Mansoureh Bolandy, Somayeh Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title | Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title_full | Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title_fullStr | Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title_full_unstemmed | Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title_short | Peripheral Primitive Neuroectodermal Tumor of the Pelvis |
title_sort | peripheral primitive neuroectodermal tumor of the pelvis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895899/ https://www.ncbi.nlm.nih.gov/pubmed/24453398 |
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