Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

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BACKGROUND: The discovery of novel anti-viral restriction factors illuminates unknown aspects of innate sensing and immunity. We identified RNA-associated Early-stage Anti-viral Factor (REAF) using a whole genome siRNA screen for restriction factors to human immunodeficiency virus (HIV) that act in...

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Detalles Bibliográficos
Autores principales: Marno, Kelly M, Ogunkolade, Babatunji W, Pade, Corinna, Oliveira, Nidia MM, O’Sullivan, Eithne, McKnight, Áine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895926/
https://www.ncbi.nlm.nih.gov/pubmed/24410916
http://dx.doi.org/10.1186/1742-4690-11-3
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