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One-pot synthesis of cyanohydrin derivatives from alkyl bromides via incorporation of two one-carbon components by consecutive radical/ionic reactions
The consecutive radical/ionic reaction consisting of radical formylation of alkyl bromides and nucleophilic addition of a cyanide ion was investigated, which gave moderate to good yields of cyanohydrin derivatives in one-pot.
Autores principales: | Sumino, Shuhei, Fusano, Akira, Okai, Hiroyuki, Fukuyama, Takahide, Ryu, Ilhyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896227/ https://www.ncbi.nlm.nih.gov/pubmed/24454568 http://dx.doi.org/10.3762/bjoc.10.12 |
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