Overactivation of Intestinal SREBP2 in Mice Increases Serum Cholesterol

Sterol Response Element Binding Protein 2 (SREBP2) transcription factor is a master regulator of cholesterol homeostasis. Treatment with statins, inhibitors of cholesterol synthesis, activates intestinal SREBP2, which may hinder their cholesterol-lowering effects. Overactivation of SREBP2 in mouse l...

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Detalles Bibliográficos
Autores principales: Ma, Ke, Malhotra, Pooja, Soni, Vinay, Hedroug, Omar, Annaba, Fadi, Dudeja, Amish, Shen, Le, Turner, Jerrold R., Khramtsova, Ekaterina A., Saksena, Seema, Dudeja, Pradeep K., Gill, Ravinder K., Alrefai, Waddah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896331/
https://www.ncbi.nlm.nih.gov/pubmed/24465397
http://dx.doi.org/10.1371/journal.pone.0084221

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