Familial Young-Onset Diabetes, Pre-Diabetes and Cardiovascular Disease Are Associated with Genetic Variants of DACH1 in Chinese

In Asia, young-onset type 2 diabetes (YOD) is characterized by obesity and increased risk for cardiovascular disease (CVD). In a genome-wide association study (GWAS) of 99 Chinese obese subjects with familial YOD diagnosed before 40-year-old and 101 controls, the T allele of rs1408888 in intron 1 of...

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Detalles Bibliográficos
Autores principales: Ma, Ronald Ching Wan, Lee, Heung Man, Lam, Vincent Kwok Lim, Tam, Claudia Ha Ting, Ho, Janice Siu Ka, Zhao, Hai-Lu, Guan, Jing, Kong, Alice Pik Shan, Lau, Eric, Zhang, Guozhi, Luk, Andrea, Wang, Ying, Tsui, Stephen Kwok Wing, Chan, Ting Fung, Hu, Cheng, Jia, Wei Ping, Park, Kyong Soo, Lee, Hong Kyu, Furuta, Hiroto, Nanjo, Kishio, Tai, E. Shyong, Ng, Daniel Peng-Keat, Tang, Nelson Leung Sang, Woo, Jean, Leung, Ping Chung, Xue, Hong, Wong, Jeffrey, Leung, Po Sing, Lau, Terrence C. K., Tong, Peter Chun Yip, Xu, Gang, Ng, Maggie Chor Yin, So, Wing Yee, Chan, Juliana Chung Ngor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896349/
https://www.ncbi.nlm.nih.gov/pubmed/24465431
http://dx.doi.org/10.1371/journal.pone.0084770

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