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Binding of HSV-1 Glycoprotein K (gK) to Signal Peptide Peptidase (SPP) Is Required for Virus Infectivity

Glycoprotein K (gK) is a virion envelope protein of herpes simplex virus types 1 (HSV-1) and 2 (HSV-2), which plays important roles in virion entry, morphogenesis and egress. Two-hybrid and pull-down assays were utilized to demonstrate that gK and no other HSV-1 genes specifically binds to signal pe...

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Detalles Bibliográficos
Autores principales:	Allen, Sariah J., Mott, Kevin R., Matsuura, Yoshiharu, Moriishi, Kohji, Kousoulas, Konstantin G., Ghiasi, Homayon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896391/ https://www.ncbi.nlm.nih.gov/pubmed/24465545 http://dx.doi.org/10.1371/journal.pone.0085360

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