Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold

The OB-fold is a small, versatile single-domain protein binding module that occurs in all forms of life, where it binds protein, carbohydrate, nucleic acid and small-molecule ligands. We have exploited this natural plasticity to engineer a new class of non-immunoglobulin alternatives to antibodies w...

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Detalles Bibliográficos
Autores principales: Steemson, John D., Baake, Matthias, Rakonjac, Jasna, Arcus, Vickery L., Liddament, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896448/
https://www.ncbi.nlm.nih.gov/pubmed/24465865
http://dx.doi.org/10.1371/journal.pone.0086050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896448/
https://www.ncbi.nlm.nih.gov/pubmed/24465865
http://dx.doi.org/10.1371/journal.pone.0086050

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