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Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold
The OB-fold is a small, versatile single-domain protein binding module that occurs in all forms of life, where it binds protein, carbohydrate, nucleic acid and small-molecule ligands. We have exploited this natural plasticity to engineer a new class of non-immunoglobulin alternatives to antibodies w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896448/ https://www.ncbi.nlm.nih.gov/pubmed/24465865 http://dx.doi.org/10.1371/journal.pone.0086050 |