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The Maternal ITPK1 Gene Polymorphism Is Associated with Neural Tube Defects in a High-Risk Chinese Population

BACKGROUND: Epidemiological surveys and animal studies have revealed that inositol metabolism is associated with NTDs, but the mechanisms are not clear. Inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) is a pivotal regulatory enzyme in inositol metabolic pathway. The objective was to assess the poten...

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Detalles Bibliográficos
Autores principales:	Guan, Zhen, Wang, Jianhua, Guo, Jin, Wang, Fang, Wang, Xiuwei, Li, Guannan, Xie, Qiu, Han, Xu, Niu, Bo, Zhang, Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896452/ https://www.ncbi.nlm.nih.gov/pubmed/24465924 http://dx.doi.org/10.1371/journal.pone.0086145

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