FOXP3-specific immunity

Forkhead box P3 (FOXP3)-specific cytotoxic CD8(+) T cells are present among human peripheral blood mononuclear cells (PBMCs), especially in cancer patients. Such T lymphocytes are able not only to specifically recognize dendritic cells (DCs) that have been exposed to recombinant FOXP3 and regulatory...

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Autor principal: Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896466/
https://www.ncbi.nlm.nih.gov/pubmed/24498544
http://dx.doi.org/10.4161/onci.26247
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author Andersen, Mads Hald
author_facet Andersen, Mads Hald
author_sort Andersen, Mads Hald
collection PubMed
description Forkhead box P3 (FOXP3)-specific cytotoxic CD8(+) T cells are present among human peripheral blood mononuclear cells (PBMCs), especially in cancer patients. Such T lymphocytes are able not only to specifically recognize dendritic cells (DCs) that have been exposed to recombinant FOXP3 and regulatory T cells, but also to kill FOXP3(+) malignant T cells. The natural occurrence of FOXP3-specific cytotoxic T lymphocytes among human PBMCs suggests a general role for these cells in the complex network of immune regulation.
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spelling pubmed-38964662014-02-04 FOXP3-specific immunity Andersen, Mads Hald Oncoimmunology Author's View Forkhead box P3 (FOXP3)-specific cytotoxic CD8(+) T cells are present among human peripheral blood mononuclear cells (PBMCs), especially in cancer patients. Such T lymphocytes are able not only to specifically recognize dendritic cells (DCs) that have been exposed to recombinant FOXP3 and regulatory T cells, but also to kill FOXP3(+) malignant T cells. The natural occurrence of FOXP3-specific cytotoxic T lymphocytes among human PBMCs suggests a general role for these cells in the complex network of immune regulation. Landes Bioscience 2013-10-01 2013-09-12 /pmc/articles/PMC3896466/ /pubmed/24498544 http://dx.doi.org/10.4161/onci.26247 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Andersen, Mads Hald
FOXP3-specific immunity
title FOXP3-specific immunity
title_full FOXP3-specific immunity
title_fullStr FOXP3-specific immunity
title_full_unstemmed FOXP3-specific immunity
title_short FOXP3-specific immunity
title_sort foxp3-specific immunity
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896466/
https://www.ncbi.nlm.nih.gov/pubmed/24498544
http://dx.doi.org/10.4161/onci.26247
work_keys_str_mv AT andersenmadshald foxp3specificimmunity

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