Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death

An early substantial loss of basal forebrain cholinergic neurons (BFCNs) is a constant feature of Alzheimer’s disease (AD) and is associated with deficits in spatial learning and memory. Induced pluripotent stem cells (iPSCs) derived from patients with AD as well as from normal controls could be eff...

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Detalles Bibliográficos
Autores principales: Duan, Lishu, Bhattacharyya, Bula J, Belmadani, Abdelhak, Pan, Liuliu, Miller, Richard J, Kessler, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896712/
https://www.ncbi.nlm.nih.gov/pubmed/24401693
http://dx.doi.org/10.1186/1750-1326-9-3

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