Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population

Toll-like receptors (TLRs), as innate immunity sensors, play critical roles in immune responses. Six SNPs of TLR3, TLR7, and TLR8 were genotyped to determine their associations with systemic lupus erythematosus (SLE) and clinical manifestations of SLE. TLR7 SNP rs3853839 was independently associated...

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Detalles Bibliográficos
Autores principales: Wang, Chin-Man, Chang, Su-Wei, Wu, Yeong-Jian Jan, Lin, Jing-Chi, Ho, Huei-Huang, Chou, Tse-Chih, Yang, Bing, Wu, Jianming, Chen, Ji-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896912/
https://www.ncbi.nlm.nih.gov/pubmed/24445780
http://dx.doi.org/10.1038/srep03792

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