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Seizure in Iranian patients with multiple sclerosis

BACKGROUND: There is a broad variation in reported frequencies of seizure in multiple sclerosis (MS). In this study, the seizure and its characteristics analyzed among a large group of patients with MS. PATIENTS AND METHODS: We reviewed the medical records of all definite MS patients referred to the...

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Autores principales: Zare, Mohammad, Norouzi, Rasul, Shayegannejad, Vahid, Ashtari, Fereshteh, Ghasemi, Majid, Tavahen, Hemaseh, Masaeli, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897021/
https://www.ncbi.nlm.nih.gov/pubmed/24516486
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author Zare, Mohammad
Norouzi, Rasul
Shayegannejad, Vahid
Ashtari, Fereshteh
Ghasemi, Majid
Tavahen, Hemaseh
Masaeli, Ali
author_facet Zare, Mohammad
Norouzi, Rasul
Shayegannejad, Vahid
Ashtari, Fereshteh
Ghasemi, Majid
Tavahen, Hemaseh
Masaeli, Ali
author_sort Zare, Mohammad
collection PubMed
description BACKGROUND: There is a broad variation in reported frequencies of seizure in multiple sclerosis (MS). In this study, the seizure and its characteristics analyzed among a large group of patients with MS. PATIENTS AND METHODS: We reviewed the medical records of all definite MS patients referred to the MS Clinic of Kashani hospital, Isfahan, Iran, between 2007 and 2011. RESULTS: Altogether, 34 cases with seizure activity identified among the 920 definite MS subjects (3.69%). Five excluded due to the other probable etiologies rather than MS. In the remained 29 patients (3.15%), the type of seizure was mostly generalized (79.3%); interictal electroencephalography showed an abnormal pattern in 84.6%, brain magnetic resonance imaging revealed subcortical white mater lesions in 84.6% of patients. The mean duration of MS onsets was 8.17 years and the mean interval between MS onset and the first seizure occurrence was 3.7 years. In general, response to antiepileptic treatment was excellent. CONCLUSION: Seizures can occur at any stage during the course of MS, but it is more common during the early stages.
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spelling pubmed-38970212014-02-10 Seizure in Iranian patients with multiple sclerosis Zare, Mohammad Norouzi, Rasul Shayegannejad, Vahid Ashtari, Fereshteh Ghasemi, Majid Tavahen, Hemaseh Masaeli, Ali J Res Med Sci Original Article BACKGROUND: There is a broad variation in reported frequencies of seizure in multiple sclerosis (MS). In this study, the seizure and its characteristics analyzed among a large group of patients with MS. PATIENTS AND METHODS: We reviewed the medical records of all definite MS patients referred to the MS Clinic of Kashani hospital, Isfahan, Iran, between 2007 and 2011. RESULTS: Altogether, 34 cases with seizure activity identified among the 920 definite MS subjects (3.69%). Five excluded due to the other probable etiologies rather than MS. In the remained 29 patients (3.15%), the type of seizure was mostly generalized (79.3%); interictal electroencephalography showed an abnormal pattern in 84.6%, brain magnetic resonance imaging revealed subcortical white mater lesions in 84.6% of patients. The mean duration of MS onsets was 8.17 years and the mean interval between MS onset and the first seizure occurrence was 3.7 years. In general, response to antiepileptic treatment was excellent. CONCLUSION: Seizures can occur at any stage during the course of MS, but it is more common during the early stages. Medknow Publications & Media Pvt Ltd 2013-07 /pmc/articles/PMC3897021/ /pubmed/24516486 Text en Copyright: © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zare, Mohammad
Norouzi, Rasul
Shayegannejad, Vahid
Ashtari, Fereshteh
Ghasemi, Majid
Tavahen, Hemaseh
Masaeli, Ali
Seizure in Iranian patients with multiple sclerosis
title Seizure in Iranian patients with multiple sclerosis
title_full Seizure in Iranian patients with multiple sclerosis
title_fullStr Seizure in Iranian patients with multiple sclerosis
title_full_unstemmed Seizure in Iranian patients with multiple sclerosis
title_short Seizure in Iranian patients with multiple sclerosis
title_sort seizure in iranian patients with multiple sclerosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897021/
https://www.ncbi.nlm.nih.gov/pubmed/24516486
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