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Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins

In myocytes, small heat shock proteins (sHSPs) are preferentially translocated under stress to the sarcomeres. The functional implications of this translocation are poorly understood. We show here that HSP27 and αB-crystallin associated with immunoglobulin-like (Ig) domain-containing regions, but no...

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Detalles Bibliográficos
Autores principales: Kötter, Sebastian, Unger, Andreas, Hamdani, Nazha, Lang, Patrick, Vorgerd, Matthias, Nagel-Steger, Luitgard, Linke, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897184/
https://www.ncbi.nlm.nih.gov/pubmed/24421331
http://dx.doi.org/10.1083/jcb.201306077